A searchable table of doubling time estimates for haploid yeast from the KO library. YPD and SC growth rates are in the BY4742 (MATαhis3Δ1 leu2Δ0 lys2Δ0 ura3Δ0) and BY4741 single-gene deletion collection (MATa; his3Δ1; leu2Δ0; met15Δ0; ura3Δ0; GeneX::kanMX) backgrounds respectively. The creator of this resource provides no guarantee of the accuracy of estimates shown here. More details below.

Haploid Deletion Library Strain Doubling Times

Below are distributions of all growth rates in the haploid deletion library in 1X YPD and SC media. Graphs have been truncated at 300 minute doubling times for ease of visibility.

Devils in the details

The data file for SC deletion growth rates did not have a WT control to compare directly doubling times, so data from Supplemental Table S7 was filtered to find WT doubling times, which had a single value of 121.95 minutes. As such, this value was used as the WT doubling time for determining relative growth rates. Used BY4742 (MATαhis3Δ1 leu2Δ0 lys2Δ0 ura3Δ0) background from Open Biosystems

Similarly, the raw data for YPD growth rates did not have a WT control to compare directly doubling times, so the WT doubling time from Table 1 in the paper was used for calculating relative doubling times. This paper only had two replicates.

Raw Data sources:

  1. Katsunori Yoshikawa, Tadamasa Tanaka, Chikara Furusawa, Keisuke Nagahisa, Takashi Hirasawa, Hiroshi Shimizu, Comprehensive phenotypic analysis for identification of genes affecting growth under ethanol stress in Saccharomyces cerevisiae, FEMS Yeast Research, Volume 9, Issue 1, February 2009, Pages 32–44, https://doi.org/10.1111/j.1567-1364.2008.00456.x

  2. Karl Persson, Simon Stenberg, Markus J Tamás, Jonas Warringer, Adaptation of the yeast gene knockout collection is near-perfectly predicted by fitness and diminishing return epistasis, G3 Genes|Genomes|Genetics, 2022;, jkac240, https://doi.org/10.1093/g3journal/jkac240